What it’s about
New research uncovers transformative insights into how high-potency cannabis can uniquely alter DNA patterns, particularly in individuals who have encountered psychosis. The study, published in Molecular Psychiatry, draws vital connections between cannabis use and genetic modifications, setting the stage for deeper understanding and preventative measures.
Why it matters
As cannabis consumption becomes more prevalent, comprehending its impacts on genetic material is crucial for identifying those at greater risk of psychotic disorders. The insights provided by this study highlight the significance of responsible use and motivate further exploration into genetic safeguarding and prevention strategies.
Details and Analysis
The collaborative research involved analyzing DNA from 239 individuals experiencing psychosis for the first time and 443 healthy volunteers across the UK, France, and Spain. Notably, 38% of these participants engaged in frequent cannabis use, with many starting at a younger age. The study seeks to understand high-potency cannabis’s genetic influence, providing evidence of DNA alterations, especially in genes governing energy and immune functions.
Key Findings
The study revealed differential DNA changes between cannabis users with and without psychotic history, emphasizing potential increased risk for psychotic disorders among frequent users. By demonstrating how cannabis and external factors impact gene functionality, these findings reinforce the need for awareness around its usage risks. Daily high-potency cannabis users, according to the study, are found to have a quintupled risk of developing psychosis compared to non-users.
Future Implications
This vital research serves as a catalyst to formulate targeted preventive strategies against psychotic diseases, bearing significant societal and healthcare implications given the rising cannabis prevalence. Recognizing these influences equips stakeholders with the tools to better educate and manage risks associated with cannabis consumption.
This story was first published on jpost.com.